Table 5.
Cohort B: Sputum Neutrophil Percentage and Supernatant Cytokine Correlations.
| Analyte | COPD, HNS, S (n = 119) |
COPD (n = 79) |
|---|---|---|
| IL-1β (pg/mL) | rho = 0.4739, p < 0.0001 | rho = 0.5136, p < 0.0001 |
| IL-1RA (pg/mL) | rho = 0.2269, p = 0.01 | rho = 0.1558, p = 0.17 |
| IL-2 (pg/mL) | rho = 0.2703, p = 0.003 | rho = 0.3399, p = 0.002 |
| IL-4 (pg/mL) | rho = 0.2676, p = 0.003 | rho = 0.3749, p = 0.0007 |
| IL-6 (pg/mL) | rho = 0.1888, p = 0.04 | rho = 0.1291, p = 0.26 |
| IL-8 (pg/mL) | rho = 0.3101, p = 0.0006 | rho = 0.4185, p = 0.0001 |
| IL-17A (pg/mL) | rho = 0.3423, p = 0.0001 | rho = 0.4318, p < 0.0001 |
| Eotaxin (pg/mL) | rho = −0.02802, p = 0.76 | rho = −0.0040, p = 0.97 |
| G-CSF (pg/mL) | rho = 0.2586, p = 0.002 | rho = 0.3600, p = 0.001 |
| IFN-γ (pg/mL) | rho = 0.3186, p = 0.0004 | rho = 0.2634, p = 0.02 |
| IP-10 (pg/mL) | rho = 0.2289, p = 0.01 | rho = 0.2981, p = 0.008 |
| MCP-1 (pg/mL) | rho = 0.1479, p = 0.1084 | rho = 0.1822, p = 0.11 |
| MIP-1α (pg/mL) | rho = 0.2732, p = 0.003 | rho = 0.3779, p = 0.0006 |
| MIP-1β (pg/mL) | rho = 0.2953, p = 0.001 | rho = 0.3959, p = 0.0003 |
| TNF-α (pg/mL) | rho = 0.3551, p < 0.0001 | rho = 0.4323, p = <0.0001 |
Data is presented as rho and p values. Results analysed using Pearson’s coefficient correlation test for parametric data and Spearman’s rank test for non-parametric data. ns: non-significant.