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Tumor, tumor microeviroment (*) and immune response signatures that are significantly overexpressed/downregulated in MSI/CD8+, MSS/CD8+ and MSI/CD8+ groups versus MSS/CD8− (reference group). Three dots are for p < 0.0001, two dots are for p = 0.0001–0.01; one dot is for p = 0.02–0.05; half dot is for p = 0.06–0.07; the arrow indicates a downregulation of the signature.
