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. 2022 Aug 16;14(16):3951. doi: 10.3390/cancers14163951

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Graphic distribution of TIS high CRCs (pink areas, TIS > 7.274) among metastatic CRCs (n = 76) considering both MSI status (MSI red arrow vs. MSS black arrow) and CD8 TIL content (CD8+ yellow circle vs. CD8− purple circle).