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. 2022 Aug 21;10(8):2043. doi: 10.3390/biomedicines10082043

Figure 1.

Figure 1

Keap1–Nrf2 Pathway. (A) basal state leading to Nrf2 degradation, (B) physiological stress/electrophiles leading to Nrf2 nuclear translocation and antioxidant transcription, (C) oxidative stress—insufficient of Nrf2 translocation/antioxidant production (created in BioRender.com, accessed on 20 July 2022).