Table 8.
Tremelimumab.
NCT Number | Status | Co-Treatment/Intervention | Phase | Participants | Results/Conclusions | References |
---|---|---|---|---|---|---|
NCT02527434 | Active, not recruiting | Monotherapy Combination therapy with MEDI4736 |
II | 12 | 1 patient completed, 11 not completed (death 6, withdrawal by subject 3, lost to follow-up 2) | [215] |
NCT03982173 | Active, not recruiting | Durvalumab | II | 88 | Estimated Study Completion Date April 2023 | [216] |
NCT02489448 | Active, not recruiting | Nab-Paclitaxel, Durvalumab (MEDI4736) | I, II | 71 | Estimated Study Completion Date December 2021 | [214] |
NCT03606967 | Recruiting | Carboplatin Durvalumab Gemcitabine Hydrochloride Nab-paclitaxel Personalized Synthetic Long Peptide Vaccine Poly ICLC |
II | 70 | No Study Results Posted | [222] |
NCT02658214 | Completed | Platinum Durvalumab |
I | 32 | No Study Results Posted | [230] |
NCT03674827 | Completed | A vaccine-based immunotherapy regimen (VBIR-2) (PF-06936308), Sasanlimab | I | 36 | No Study Results Posted | [239] |