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. 2022 Aug 12;10(8):1964. doi: 10.3390/biomedicines10081964
ANP atrial natriuretic peptide
AT angiotensin
BP blood pressure
BW body weight
CAP captopril (60 mg kg−1 d−1)
CAP + NIF captopril plus nifedipine (60 + 10 mg kg−1 d−1)
Coll I collagen type I
Coll III collagen type III
CTRL untreated hypertensive control rats
ECM extracellular matrix
GAP-DH glyceraldehyde-3-phosphate dehydrogenase
HW heart weight
LV left ventricle, left ventricular
MMP-2 matrix metalloproteinase 2
NIF nifedipine (10 mg kg−1 d−1)
RAAS renin-angiotensin-aldosterone-system
SBP systolic blood pressure
SHR spontaneously hypertensive rats
TGF-β Transforming Growth Factor-β
TIMP-2 tissue inhibitor of metalloproteinases 2