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View full-text article in PMC

. 2022 Aug 17;14(16):3975. doi: 10.3390/cancers14163975

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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In silico analysis of the antigens revealed the levels of expression in normal tissues. Target antigens derived from p53-R175H and p53-R273H mutants and common to both HLA fractions (Pan-HLA and HLA-A2) were checked for their normal tissue expression. Heatmap showing the expression levels of each protein in normal cells. The purple, red and orange colors indicate very high to low levels of expression, pale yellow represents no expression detected, and white represents no data available in the corresponding histology in Human Protein Atlas.