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. 2022 Aug 11;11(16):2490. doi: 10.3390/cells11162490

Figure 2.

Figure 2

Conditioned media from CRC cells have no impact on fibroblast expression of ECM components, but show some effects on the expression of MMPs. (A) Relative expression levels of ECM components Fn1, Col1A1, Col3A1 and Col4A1, and(B) MMPs 1, 2, 3 and 14. Values of the independent experiments (represented as black squares) were normalized to the DMEM control and were plotted as mean ± SD. Data normality was tested using the Shapiro–Wilk test and a parametric or non-parametric t-test was performed in accordance, comparing all conditions with the DMEM control (* p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001).