Table 2.
Case reports reported in the literature show non-syndromic familial tendency mesiodens.
| Study | Family Bond with Supernumerary Teeth | Mesiodens | Age at Diagnosis | Complications |
|---|---|---|---|---|
| Sedano et al., 1969 [13] | Sister Brother |
Sister: Mesiodens inverted Brother: Mesiodens without inversion |
Not reported | Sister: The root development was not fully completed Brother: There were no alterations |
| Beere et al., 1990 [14] | Monozygotic, male | Twin 1: Supplementary primary maxillary lateral incisor on the right side Twin 2: Supplementary primary maxillary incisor on the left side |
4 years old | Erupted mesiodens |
| Choi et al., 1990 [15] | Monozygotic, male | Bilateral mesiodens of opposite orientation Mesiodent roots were fully formed |
10 years old | Three conical and impacted mesiodens, one in incisiform eruption |
| Almeida et al., 1995 [16] | Three siblings | Sibling 1: Presence of an erupted mesiodens Sibling 2: Radiographically, intraosseous mesiodens between the upper incisors were observed Sibling 3: Radiographically revealed an intraosseous development mesiodens |
Sibling 1: 11 years old Sibling 2: 9 years old Sibling 3: 21 years old |
Sibling 1: Teeth 11 and 21 were poorly positioned Sibling 2: Radiographically detected without complication Sibling 3: Radiographically detected without complication |
| Seddon et al., 1997 [17] | Monozygotic, male Grandmother |
Both twins with bilateral mesiodens Twin 1: The right mesiodens was large with a barrel-shaped crown. The left mesiodens was more incisiform Twin 2: The right mesiodens was conical in form. The left mesiodens was more incisiform Grandmother: Presence of mesiodens |
Twins: 7 years old Grandmother: Not reported |
Twins: Retained primary central incisors Grandmother: Not reported |
| Marya et al., 1998 [18] | Two siblings | Sibling 1: Presence of two conical mesiodens eruptions The right mesiodens had a small notehlike projection Sibling 2: Molariform mesiodens eruptions, with five cusps. An intraoral oclusal radiograph revealed the presence of a second, unerupted supernumerary mesiodens |
Sibling 1: 12 years old Sibling 2: 8 years old |
Sibling 1: Revealed that the maxillary central incisors were positioned far apart because of the presence of two conical mesiodens eruptions. Both permanent maxillary canines were clinically absent Sibling 2: The maxillary left central incisor was malpositioned, the mesiodens was occluding with the mandibular left central incisor and caused a maxillary midline diastema of 4 mm |
| Gallas et al., 2000 [19] | Two sisters | Both sisters with 2 supernumerary teeth in the position of the central incisors | Sister 1: 13 years old Sister 2: 8 years old |
Sister 1: Retention of permanent incisors Sister 2: The permanent central incisors had erupted without the deciduous central incisors having exfoliated |
| Sharma et al., 2008 [20] | Monozygotic, male | Twin 1: Intraoral examination palatally erupting tuberculate mesiodens in relation to 61. Radiographic examination revealed bilateral presence of two tuberculate mesiodens, one erupted and causing rotation of 21, while the other was seen impacted in relation to 51 Twin 2: Clinical and radiographic examination showed a tuberculate mesiodens between the primary central incisors |
7 years old | Twin 1: Complaint of a tooth seen to be erupting for the last 3 months behind the upper front teeth and causing difficulty while speaking Twin 2: Maxillary midline supernumerary tooth which was erupting for the last 2 months |
| Verma et al., 2010 [21] | Case report 1: sister and brother Case report 2: father and son |
Case 1: Intraoral examination revealed two palatally erupting diverging tuberculate mesiodens behind 11 and 21. Intraoral periapical radiograph of 11 and 21 region showed well-defined tuberculate mesiodens with fully formed roots Case 2: Son: A palatally erupted tuberculate mesiodens Father: Fused mesiodens |
Case 1 Brother 1: 14 years Brother 2: 11 years Case 2: Son: 11 years old Father: Not reported |
Case 1: Mesiodens erupting behind the upper front teeth, revealed recurrent injury to the tongue while making tongue movements. Additionally, there is lodgment of food between upper front teeth and erupting extra teeth leading to difficulty in chewing food Case 2: Son: Tooth erupting behind upper front teeth leading to malalignment of teeth in the upper front teeth region. Displacement of 2.1 Father: Affectation of 1.1 |
| Babacan et al., 2010 [22] | Monozygotic, male | Mesiodens were palatal to the impacted central incisors | 10.5 years old | Mesiodens was preventing eruption of the maxillary left central incisor in both twins. Space loss and midline shift of the right central incisor had occurred, and the left lateral incisors had drifted mesially in both children |
| Sadeghzadeh-Araghi et al., 2019 [23] | Father Son |
Father: Mesiodens between roots of central incisors with an unintentional coronectomy, the crown of the tooth had been removed as it was mistaken for a bony growth/extension of the anterior nasal spine Son: Mesiodens was lying behind the anterior nasal spine, buccally positioned and in close proximity to both the floor of the left nasal aperture and maxillary incisor apices |
Father: 65 years old Son: 17 years old |
Father: Dull ache around the anterior maxilla Son: Radiographic finding, asymptomatic |
| Witanowska et al., 2011 [24] | Monozygotic twin sisters | Incisiform mesiodens with its root developed; root tip in maxillary midline, mesiodens left tilted, its crown within eruption pathway | 8 years 5 months |
|