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A schematic picture showing some of the main components of CAs, the interaction of cell cycle kinase CDK1 with talin, and the central adhesion-dependent events regulating the G1 to S transition. Paxillin both links kindlin to the GTP-Rap1-activated talin and recruits FAK to the complex. Integrin α-units are shown in blue and the β-units are in white. The red lines represent the extracellular matrix.
