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. 2022 Aug 18;11(16):2564. doi: 10.3390/cells11162564

Table 1.

Expressions of AQPs in cerebral cortex, cerebellum, choroid plexus, brain cells and neural stem cells.

AQP Isoforms Cerebral Cortex Cerebellum Choroid Plexus Astrocyte Oligodendrocyte Neuron Neural Stem Cell
AQP1 Yes [48] Yes [49] Yes [48,50] Yes [48] - Yes [48] -
AQP3 Yes [51,52] Yes [52] Yes [52] Yes [51,52] - Yes [51,52] -
AQP4 Yes [53,54] Yes [54] - Yes [41,53,54] - - Yes [41,42]
AQP5 Yes [52,53] Yes [52] Yes [52,55] Yes [53] - Yes [52] -
AQP6 - Yes [56] - - - Yes [57] -
AQP7 - - Yes [58] - - - -
AQP8 Yes [51,52] Yes [52] Yes [52] Yes [51,52] Yes [51] Yes [51,52] Yes [59]
AQP9 Yes [60] Yes [61] - Yes [60,61] - Yes [61,62] Yes [41]
AQP11 Yes [63,64] Yes [65] Yes [64,65] - - Disputed [63,64] -

AQP expressions are summarized for the three brain areas on which most studies on AQPs in the CNS are focused. Microglia are not included as they are related to the macrophage/monocyte lineage. Expressions of AQPs are based on detection of either mRNA or protein.