Table 1.
AQP Isoforms | Cerebral Cortex | Cerebellum | Choroid Plexus | Astrocyte | Oligodendrocyte | Neuron | Neural Stem Cell |
---|---|---|---|---|---|---|---|
AQP1 | Yes [48] | Yes [49] | Yes [48,50] | Yes [48] | - | Yes [48] | - |
AQP3 | Yes [51,52] | Yes [52] | Yes [52] | Yes [51,52] | - | Yes [51,52] | - |
AQP4 | Yes [53,54] | Yes [54] | - | Yes [41,53,54] | - | - | Yes [41,42] |
AQP5 | Yes [52,53] | Yes [52] | Yes [52,55] | Yes [53] | - | Yes [52] | - |
AQP6 | - | Yes [56] | - | - | - | Yes [57] | - |
AQP7 | - | - | Yes [58] | - | - | - | - |
AQP8 | Yes [51,52] | Yes [52] | Yes [52] | Yes [51,52] | Yes [51] | Yes [51,52] | Yes [59] |
AQP9 | Yes [60] | Yes [61] | - | Yes [60,61] | - | Yes [61,62] | Yes [41] |
AQP11 | Yes [63,64] | Yes [65] | Yes [64,65] | - | - | Disputed [63,64] | - |
AQP expressions are summarized for the three brain areas on which most studies on AQPs in the CNS are focused. Microglia are not included as they are related to the macrophage/monocyte lineage. † Expressions of AQPs are based on detection of either mRNA or protein.