Figure 4.
Urolithins A and B differentially affected the viability of podocytes exposed to high glucose. Podocytes cultured in high glucose (25 mM, HG) were incubated for 48 h with varying concentrations of urolithins. Control cells were incubated with vehicle (DMSO) alone. Results show mean ± SEM. ANOVA and the Student’s t-tests were used to calculate p values. * p < 0.05 vs. NG Control, & p < 0.05 vs. 30 µM UB, ** p < 0.01 vs. NG Control and vs. 100 µM UB, # p < 0.005 vs. HG Control and vs. 10 µM UB. Each MTT test was performed in quadruplicate (n = 4).