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. 2022 Aug 22;29(8):5963–5987. doi: 10.3390/curroncol29080471

Figure 3.

Figure 3

CTSK can promote the proliferation, invasion and migration of different types of breast cancer cells, especially bone metastasis. There are multiple signaling pathways involved in this process, including RANKL/RANK signaling, NF-κB signal pathways, TGF-β and mTOR signal pathways.