Figure 8.

H19 knockout mice displayed anterior polar cataracts and delayed anterior suture fusion. (a–h) Photos were taken under slit lamps after the mice were anesthetized and their pupils were dilated. The ocular lenses of 8-week H19 (-/-) mice and the wild-type littermates were examined in-vivo by Haag-Streit BX 900 slit lamp with a diffuse illumination mode (a,b), a narrow slit mode (c,d), a moderate slit mode (e,f), and a retro-illumination mode (g,h). (i,j) Photos of freshly enucleated lenses from 8-week H19 (-/-) mice and the wild-type littermates. Observations in both eyes were similar, and representative pictures of one eye were shown here. Scale bars, 0.5 mm.