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. 2022 Aug 22;14(16):4052. doi: 10.3390/cancers14164052

Table 1.

WHO grading of CNS and brain tumors.

Grading Some Selected Types of CNS and Brain Tumor
Grade 1 Meningioma, solitary fibrous tumor, diffuse astrocytoma (MYB- or MYBL1-altered), polymorphous low-grade neuroepithelial tumor of the young, multi-nodular and vacuolating neuronal tumor.
Grade 2 Meningioma, solitary fibrous tumor, oligodendroglioma, astrocytoma (IDH-mutant), IDH-mutant, and 1p/19q-co-deleted, myxopapillary ependymoma, pleomorphic xanthoastrocytoma, supratentorial ependymoma, posterior fossa ependymoma.
Grade 3 Meningioma, solitary fibrous tumor, oligodendroglioma, Astrocytoma (IDH-mutant), IDH-mutant, and 1p/19q-co-deleted, pleomorphic xanthoastrocytoma, supratentorial ependymoma posterior fossa ependymoma.
Grade 4 Glioblastoma (IDH-wildtype), astrocytoma (IDH-mutant), diffuse hemispheric glioma (H3 G34-mutant).