| 1-MT | 1-methyl-D-tryptophan |
| 3-HKYN | 3-hydroxykynurenine |
| AhR | aryl hydrocarbon receptor |
| AKI | acute kidney injury |
| AP-1 | activator protein 1 |
| APCs | antigen-presenting cells |
| ATP | adenosine triphosphate |
| BTK | Bruton’s tyrosine kinase |
| CCI | cecal content injection |
| CLP | cecal ligation, puncture |
| CpG-DNA | cytosine-phosphate-guanine dinucleotides present in bacterial DNA |
| CVVH | continuous veno-venous haemofiltration |
| CXCL1 | C-X-C Motif Chemokine Ligand 1 |
| CXCR2 | C-X-C Motif Chemokine Receptor 2 |
| DAMPs | damage-associated molecular patterns |
| DCs | dendritic cells |
| FLT3L | FMS-related tyrosine kinase 3 ligand |
| fMLP | N-formyl-methionyl-leucyl-phenylalanine |
| GCN2K | general control nonderepressible 2 kinases |
| GFR | glomerular filtration rate |
| GM-CSF | granulocyte-macrophage colony-stimulating factor |
| HMGB1 | high-mobility group box 1 |
| i.v. | intravenously |
| ICAM-1 | intercellular adhesion molecule 1 |
| ICU | intensive care unit |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| IDO2 | indoleamine 2,3-dioxygenase 2 |
| IFN-ɣ | interferon-gamma |
| IGFBP7 | insulin-like growth factor-binding protein 7 |
| IL-12 | interleukin 12 |
| IL-17A | interleukin-17A |
| IL-6 | interleukin 6 |
| IL-8 | interleukin 8 |
| iNOS | inducible nitric oxide synthase |
| IRAKM | IL-1 receptor-associated kinase M |
| ITK | IL-2 inducible T-cell kinase |
| KP | kynurenine pathway |
| KYN | kynurenine |
| KYNA | kynurenic acid |
| LPS | lipopolysaccharide |
| Mac-1 | macrophage-1 antigen |
| MCP-1 | monocyte chemoattractant protein-1 |
| MIF | migration inhibitory factor |
| MPO | myeloperoxidase |
| mtDNA | mitochondrial DNA |
| mTOR | mammalian target of rapamycin |
| MyD88 | Myeloid Differentiation Factor 88 |
| NETs | neutrophil extracellular traps |
| NFAT | nuclear factor of activated T cells |
| NF-κB | nuclear factor kappa-light-chain-enhancer of activated B cells |
| NGAL | neutrophil gelatinase-associated lipocalin |
| NK | natural killer |
| NLRs | nucleotide-binding oligomerization domain-like receptors |
| NOX-2 | neutrophils possess enzymes-NADPH oxidase |
| PAMPs | pathogen-associated molecular patterns |
| PDL1 | programmed death-ligand 1 |
| PPAR-α | peroxisome proliferator-activated receptor α |
| QUIN | quinolinic acid |
| ROS | reactive oxygen species |
| RTECs | renal tubular epithelial cells |
| SAKI | sepsis-induced AKI |
| SIRS | systemic inflammatory response syndrome |
| STAT3 | signal transducer and activator of transcription 3 |
| Syk | spleen tyrosine kinase |
| TDO2 | tryptophan 2,3-dioxygenase 2 |
| TGF-β | transforming growth factor β |
| Th17 | T helper 17 |
| Th2 | T helper 2 |
| TIMP-2 | tissue inhibitor of metalloproteinase-2 |
| TLR4 | Toll-like receptor 4 |
| TLRs | Toll-like receptors |
| TNF-α | tumor necrosis factor α |
| Tregs | regulatory T cells |
| TRP | trypthofan |
| VCAM-1 | vascular cell adhesion molecule 1 |
| WT | Wild-type mice |