Table 2.
Diagnostic performance of AI-CACS with manual CACS as reference. Data are shown per patient and per coronary artery.
| Per Patient | Per Coronary Artery | ||||
|---|---|---|---|---|---|
| All Patients | LM | LAD | RCX | RCA | |
| Sensitivity | 85.0% (77.2–92.8%) |
74.5% (62.5–86.5%) |
82.0% (73.4–91.0%) |
64.2% (51.2–77.1%) |
61.7% (49.4–74.0%) |
| Specificity | 90.0% (76.9–100%) |
79.6% (68.3–90.9%) |
100% (100–100%) |
95.7% (90.0–100%) |
95.0% (88.2–100%) |
| Diagnostic accuracy | 86.0% (77.6–92.1%) |
77.0% (67.5–84.8%) |
87.0% (78.8–92.9%) |
79.0% (69.7–86.5%) |
75.0% (65.3–83.1%) |
| PPV | 97.1% (93.2–100%) |
79.2% (67.7–90.7%) |
100% (100–100%) |
94.4% (87.0–100%) |
94.9% (88.0–100%) |
| NPV | 60.0% (42.5–77.5%) |
75.0% (63.2–86.8%) |
67.5% (53.0–82.0%) |
70.3% (59.1–81.5%) |
62.3% (50.1–74.4%) |
| Total, n | 100 | 100 | 100 | 100 | 100 |
| True positive, n | 68 | 38 | 60 | 34 | 37 |
| False negative, n | 12 | 13 | 13 | 19 | 23 |
| True negative, n | 18 | 39 | 27 | 45 | 38 |
| False positive, n | 2 | 10 | 0 | 2 | 2 |
LM left main, LAD left anterior descending, RCX ramus circumflex, RCA right coronary artery, PPV positive predictive value, NPV negative predictive value. Data are presented as sensitivity, specificity, diagnostic accuracy, PPV, and NPV % (95% confidence interval).