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Effects of trametinib and dabrafenib on DU-4475 cell viability and death. (a) Growth curves of DU-4475 treated with different concentrations of trametinib over time. (b) Dose–response curves of DU-4475 treated with trametinib for 1 h and 48 h. (c) Dose–response curves of DU-4475 treated with dabrafenib for 1 h and 48 h. (d) Western blots of full length and cleaved caspases, PARP, and β-actin. Uncropped Western Blots and densitometry can be found at supplementary.
