Table 1.
Quantitative evaluations of DeepContrast models.
| Model | Evaluation | Region | Data | PSNR | P.R | S.R | SSIM |
|---|---|---|---|---|---|---|---|
| Healthy | Similarity | Whole Brain | Gd-Uptake vs. T2W | 22.16 ± 0.59 | –0.072 ± 0.032 | 0.074 ± 0.013 | 0.707 ± 0.007 |
| Mouse | Gd-Uptake vs. Gd-Predicted | 24.59 ± 0.60 | 0.695 ± 0.008 | 0.606 ± 0.008 | 0.831 ± 0.008 | ||
| Healthy | Similarity | Whole Brain | Gd-Uptake vs. T1W | 15.40 ± 0.09 | –0.194 ± 0.003 | –0.323 ± 0.005 | 0.446 ± 0.002 |
| Human | Gd-Uptake vs. Gd-Predicted | 29.64 ± 0.07 | 0.822 ± 0.002 | 0.625 ± 0.003 | 0.879 ± 0.002 | ||
| White Matter | Gd-Uptake vs. T1W | 15.40 ± 0.09 | –0.194 ± 0.003 | –0.323 ± 0.005 | 0.446 ± 0.002 | ||
| Gd-Uptake vs. Gd-Predicted | 35.15 ± 0.09 | 0.633 ± 0.006 | 0.437 ± 0.002 | 0.969 ± 0.001 | |||
| Gray Matter | Gd-Uptake vs. T1W | 14.72 ± 0.06 | –0.029 ± 0.002 | –0.039 ± 0.003 | 0.462 ± 0.001 | ||
| Gd-Uptake vs. Gd-Predicted | 30.18 ± 0.07 | 0.807 ± 0.004 | 0.510 ± 0.003 | 0.946 ± 0.001 | |||
| CSF | Gd-Uptake vs. T1W | 20.65 ± 0.07 | 0.124 ± 0.003 | 0.120 ± 0.004 | 0.802 ± 0.003 | ||
| Gd-Uptake vs. Gd-Predicted | 25.47 ± 0.08 | 0.728 ± 0.004 | 0.604 ± 0.003 | 0.936 ± 0.001 | |||
| Test-Retest | Whole Brain | Gd-Uptake of two repeated acquisitions | 27.70 ± 0.24 | 0.815 ± 0.007 | 0.415 ± 0.017 | 0.832 ± 0.007 | |
| Reliability | Gd-Predicted of two repeated acquisitions | 30.11 ± 0.44 | 0.919 ± 0.005 | 0.722 ± 0.010 | 0.948 ± 0.002 | ||
| White Matter | Gd-Uptake of two repeated acquisitions | 31.18 ± 0.18 | 0.713 ± 0.015 | 0.129 ± 0.008 | 0.933 ± 0.004 | ||
| Gd-Predicted of two repeated acquisitions | 35.14 ± 0.40 | 0.899 ± 0.006 | 0.368 ± 0.014 | 0.986 ± 0.001 | |||
| Gray Matter | Gd-Uptake of two repeated acquisitions | 27.89 ± 0.32 | 0.844 ± 0.008 | 0.327 ± 0.020 | 0.907 ± 0.005 | ||
| Gd-Predicted of two repeated acquisitions | 30.42 ± 0.44 | 0.937 ± 0.004 | 0.596 ± 0.013 | 0.976 ± 0.001 | |||
| CSF | Gd-Uptake of two repeated acquisitions | 24.04 ± 0.27 | 0.762 ± 0.014 | 0.585 ± 0.019 | 0.907 ± 0.004 | ||
| Gd-Predicted of two repeated acquisitions | 26.32 ± 0.48 | 0.882 ± 0.009 | 0.800 ± 0.008 | 0.967 ± 0.001 |
Evaluations varied depending on the aspects being assessed for each model. All metrics were reported in the form of mean ± standard error of the mean (SEM). PSNR, peak signal-to-noise ratio; P.R, Pearson correlation coefficient; S.R, Spearman correlation coefficient; SSIM, structural similarity index.