Table 1.
Mutant XPA proteins used in this study
| Name | XPA mutation | RPA binding site |
|---|---|---|
| M32-1 | R34E | 32C |
| M32-3 | R34E/R39E/R42E | 32C |
| M32-4 | R30E/K31E/R32E/R34E | 32C |
| M32-6 | R30E/K31E/R32E/R34E/R39E/R42E | 32C |
| M70-1K | E106K | 70AB |
| M70-1A | F112A | 70AB |
| M70-2 | E106K/F112A | 70AB |
| M70-4 | D101N/E106K/K110E/F112A | 70AB |
| M70-6 | D101N/E106K/K110E/E111K/F112A/D114N | 70AB |
| M32-1/70-1 | R34E/F112A | 32C and 70AB |
| M32-1/70-2 | R34E/E106K/F112A | 32C and 70AB |
| M32-3/70-2 | R34E/R39E/R42E/E106K/F112A | 32C and 70AB |
| M32-4/70-2 | R30E/K31E/R32E/R34E/E106K/F112A | 32C and 70AB |
All XPA mutants in this study are named by labeling the binding site in RPA to which they are directed (RPA32C or RPA70AB) and the number of mutations made.