Table 1.
Biologic parameters in study group and control group.
| Parameter | Admission DateMedian [Q1, Q3] | Follow-Up (3 Months) Median [Q1, Q3] | Control Group Median [Q1, Q3] | p-Value Admission vs. Follow-Up | p-Value Follow-Up vs. Control |
|---|---|---|---|---|---|
| C reactive protein (mg/L) | 43.9 [12.8, 89.9] | 3.35 [1.85, 6,49] | 2.8 [2.3, 3.6] | <0.001 | 0.794 |
| Erythrocyte Sedimentation Ratio (mm/h) | 45.8 [18.9, 60.7] | 15 [12, 17] | 14 [11, 16] | <0.001 | 0.570 |
| Fibrinogen (mg/dL) | 479 [368.8, 609.5] | 344 [307, 413.5] | 303.5 [244, 340.25] | <0.001 | 0.007 |
| Lactate dehydrogenase (U/L) | 279.2 [230.7, 365.1] | 188 [168, 214] | 180.5 [160, 197.75] | <0.001 | 0.419 |
| Alanine transaminase (U/L) | 42.2 [28, 57.6] | 37.5 [32, 47.7] | 36 [31.5, 39.5] | <0.001 | 0.151 |
| Creatine kinase (U/L) | 112.5 [48, 166.7] | 71.5 [36.7, 182] | 75 [41, 127] | 0.222 | 0.144 |
| Erythrocytes (×106/µL) | 4.68 [4.2, 5] | 4.7 [4.3, 5.1] | 4.64 [4.28, 5] | 0.665 | 0.519 |
| Leukocytes (×103/µL) | 6.6 [5.3, 10] | 7.1 [5.8, 9.1] | 6.6 [5.5, 9.1] | 0.096 | 0.644 |
| Lymphocytes (×103/µL) | 1 [0.6, 1.6] | 1.5 [1.1, 2.1] | 1.5 [1.3, 2] | 0.746 | 0.998 |
| Neutrophils (×103/µL) | 4.9 [3.4, 7.5] | 4.1 [3.2, 4.5] | 4.1 [3.2, 4.4] | <0.001 | 0.925 |
| Ly/Ne ratio | 0.2 [0,1, 0,4] | 0.4 [0.3, 0.5] | 0.4 [0.3, 0.5] | 0.383 | 0.9 |
| Platelets (×103/µL) | 203.3 [150.7, 256] | 223 [173.5, 301.7] | 225 [186, 280.5] | 0.614 | 0.937 |
| Ferritin (ng/mL) | 667.1 [319.4,1236.6] | 285 [150, 409.6] | 238 [150, 373.6] | <0.001 | 0.603 |
| D-dimers (ng/mL) | 204 [148.5, 287.2] | 210 [154, 283.5] | 201 [153.2, 257] | 0.111 | 0.658 |
| IL-1 (pg/mL) | 4.19 [0.2, 14.2] | 3.7 [0.4, 9.8] | 2.6 [0.3, 5.8] | 0.058 | 0.763 |
| IL-6 (pg/mL) | 68.6 [34.3, 249.1] | 8.7 [4.4, 24.2] | 5.1 [3.3, 7] | <0.001 | 0.814 |
Q1-first quartile, Q3-third quartile.