Table 3.
Risk factors associated with pulmonary fibrosis in patients at hospital admission.
| Parameter | Spearman’s Rho | p-Value | OR [CI] | Risk of Fibrosis |
|---|---|---|---|---|
| Age | 130 | 0.198 | ||
| CRP | 0.252 | 0.02 | 1.015 [1.002, 1.028] | 1.5% * |
| ESR | 0.422 | <0.001 | 1.057 [1.021, 1.094] | 5.7% * |
| Fibrinogen | 0.192 | 0.06 | ||
| LDH | 0.204 | 0.05 | 1.005 [1, 1.01] | 0.5% * |
| Alanine transaminase | 0.135 | 0.19 | ||
| Creatine kinase | −0.74 | 0.47 | ||
| Erythrocytes | 0.007 | 0.94 | ||
| Leukocytes | 0.122 | 0.234 | ||
| Lymphocytes | 0.102 | 0.321 | ||
| Neutrophils | 0.076 | 0.457 | ||
| Ly/Ne ratio | 0.052 | 0.615 | ||
| Ferritin | −0.077 | 0.518 | ||
| Platelets | 0.152 | 0.137 | ||
| D-dimers | 0.12 | 0.25 | ||
| IL-1 | −0.206 | 0.302 | ||
| IL-6 | 0.192 | 0.145 | ||
| Duration of hospitalization | 0.249 | 0.012 | 1.06 [1.008, 1.115] | 6% * |
| Duration of antiviral treatment | 0.246 | 0.019 | 1.089 [0.957, 1.239] | − |
| Number of affected pulmonary lobes | 0.252 | 0.012 | 1.82 [1.175, 2.818] | 82% * |
| Percent of alveolar consolidation | 0.389 | <0.001 | 1.124 [0.776, 1.628] | − |
| Percent of mixed pulmonary lesions | 0.357 | <0.001 | 1.089 [0.917, 1.295] | − |
| Percent of interstitial pulmonary lesions | 0.519 | <0.001 | 1.122 [1.065, 1.183] | 12.2% * |
| Percent of normal lung densities | −0.478 | <0.001 | 0.924 [0.888, 0.761] | 8.6% # |
| Total pulmonary lung lesions | 0.480 | <0.001 | 1.081 [1.04, 1.124] | 8.1% * |
* For a 1 unit increase in the parameter; # for 1 unit decrease in the parameter.