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. 2022 Aug 15;12(8):1082–1107. doi: 10.3390/ejihpe12080077

Table 5.

Multivariable associations for DASS-21 subscales.

Adjusted OR
(95% CI)
p-Value
Multivariable Associations for the Depression Subscale—n = 561
Mild to moderate vs. Normal
Smoking No Reference
<10 cigarettes per day and/or <3 shisha per week 1.14 (0.58; 2.25) 0.7
≥10 cigarettes per day and/or ≥3 shisha per week 2.72 (1.13; 6.54) 0.03
Feel isolated from others due to COVID-19 Never Reference
Rarely 1.67 (0.80; 3.50) 0.2
Usually 2.47 (1.23; 4.95) 0.01
Always 4.21 (1.87; 9.46) 0.001
Taking other drugs # 2.12 (1.06; 4.28) 0.04
Severe to extremely severe vs. Normal
Smoking No Reference
<10 cigarettes per day and/or <3 shisha per week 1.009 (0.46; 2.22) 0.9
≥10 cigarettes per day and/or ≥3 shisha per week 3.32 (1.30; 8.52) 0.01
Body weight during COVID-19 No changes Reference
Gained weight 2.37 (1.22; 4.63) 0.01
Lost weight 3.47 (1.80; 6.67) <0.001
Taking other drugs # 3.93 (1.84; 8.38) <0.001
Feel isolated due to COVID-19 Never Reference
Rarely 1.009 (0.33; 3.08) 0.9
Usually 5.32 (1.99; 14.2) 0.001
Always 11.1 (3.84; 32) <0.001
Multivariable associations for the anxiety subscale—n = 561
Mild to moderate vs. Normal
Feel isolated due to COVID-19 Never Reference
Rarely 1.70 (0.80; 3.62) 0.2
Usually 2.01 (1.01; 4.23) 0.047
Always 1.76 (0.77; 4.01) 0.2
Severe to extremely severe vs. Normal
Body weight during COVID-19 No changes Reference
Gained weight 1.55 (0.86; 2.80) 0.1
Lost weight 1.83 (1.03; 3.25) 0.04
Year in pharmacy school First or second Reference
Third or fourth 1.30 (0.73; 2.30) 0.4
Fifth or PharmD 0.5 (0.28; 0.92) 0.03
Taking multivitamins or minerals 1.86 (1.07; 3.21) 0.03
Feel isolated due to COVID-19 Never Reference
Rarely 1.20 (0.51; 2.82) 0.7
Usually 2.65 (1.21; 5.79) 0.02
Always 3.11 (1.32; 7.32) 0.009
Multivariable associations for the stress subscale—n = 561
Mild to moderate vs. Normal
Smoking No Reference
<10 cigarettes per day and/or <3 shisha per week 1.16 (0.60; 2.25) 0.7
≥10 cigarettes per day and/or ≥3 shisha per week 3.01 (1.42; 6.62) 0.004
Body weight during COVID-19 No changes Reference
Gained weight 1.55 (0.90; 2.64) 0.1
Lost weight 1.85 (1.12; 3.08) 0.02
Year in pharmacy school First or second Reference
Third or fourth 1.82 (1.10; 3.02) 0.02
Fifth or PharmD 0.88 (0.5; 1.54) 0.7
Feel isolated due to COVID-19 Never Reference
Rarely 1.61 (0.74; 3.51) 0.2
Usually 2.28 (1.10; 4.71) 0.03
Always 2.09 (0.93; 4.69) 0.07
Severe to extremely severe vs. Normal
Body weight during COVID-19 No changes Reference
Gained weight 2.21 (1.05; 4.67) 0.04
Lost weight 3.11 (1.53; 6.32) 0.002
Taking antidepressants and/or anxiolytics 11.16 (1.94; 64.4) 0.007
Feel isolated due to COVID-19 Never Reference
Rarely 1.27 (0.30; 5.35) 0.7
Usually 4.81 (1.34; 17.3) 0.02
Always 7.10 (1.90; 26.6) 0.004

# Others = other than acetaminophen, antihistamines, NSAIDs, multivitamins or minerals, antidepressants or anxiolytics; COVID-19, Coronavirus disease 2019; NSAIDs, Non-Steroidal Anti-Inflammatory Drugs; CI, Confidence interval.