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. 2022 Jul 31;13(8):1374. doi: 10.3390/genes13081374

Table 2.

Immunophenotypic features of studied genetic subtypes.

Antigen ETV6::RUNX1 BCR::ABL1 KMT2A TCF3::PBX1 Hyper-Diploidy Prognosis if + EGIL Subtype if +
CD10 + [32,33,35,47,62] + [6,22,32,34] − [10,13,32,33,59] +/− [13,32] + [11,32] Good [26] B-II [13,31]
CD66c − [13,32,38,73] + [13,21,32,37,38,39] − [6,32,38] − [32,38] + [11,32,33] Inconclusive Irrelevant
NG2 − [32] − [32] + [10,25,26,32,33] − [32] [32] Poor [3,25,26] B-I [10,26,32]
TSLPR ND ND ND ND ND Poor [24,42,43] Irrelevant
CD123 Low + [45] + [44] + [6] − [6] + [1,33,44,45,46,74] Good [3,45] B-II [45]
CD9 − [6,13,14,32,47] + [6] + [6,32] + [6,32] ND Poor [14,47] Irrelevant
CD38 + [1,33] − [6,34] + [6] + [6] − [1] Inconclusive [1,50] Irrelevant
CD45 Low+ [16,32,33,62] −/Low+ [32] Low+ [32] Low + [32] − [11,32,53] Poor [4,51,52] Irrelevant
CD20 − [13,16,32,62] + [32] − [6,13,32,59] Low + [13,32] Low+ [32] Inconclusive [39,54] Irrelevant
CD24 + [13,32] + [13,32] − [13,26,32,33] + [32] + [32] Inconclusive B-IV [56,57]
CD22 Low+ [32] Low+ [32] − [32,59] + [32] + [32] Inconclusive All [13,31]
CD13 + [13,22,32] + [16,32,34,39,62] − [32] − [32] − [32] Inconclusive Irrelevant
cIgM − [32] − [32] − [6,32] + [6,10,15,32] − [32] Poor B-III [13,31,63,64]
CD15 − [32,62] − [6,32,39] + [6,10,13,26,32,59] − [32] − [32] Poor B-I [13]
CD33 + [13,32] + [13,22,39] − [32] − [32] − [32] Poor [1] Irrelevant
TdT + [13,32] + [13,32] Low+ [33]/ + [13,32] +[32] +[32] Inconclusive B-I, II, III [13,31]
CD81 Low+/−[33] ND − [33] ND − [33] Good Irrelevant
CD34 Low+ [33]/ + [6,13,32,62] + [6,13,34] − [6,32,33] − [6,13,32] + [32,33] Inconclusive Irrelevant