A) Change in 8-isoprostane levels (marker of oxidative stress to lipids) after 8-weeks of intervention for the 4-h TRF, 6-h TRF and Ad lib control group.
B) Change in plasma TNF-alpha levels after 8-weeks of intervention for the 4-h TRF, 6-h TRF and Ad lib control group.
C) Change in plasma IL-6 levels after 8-weeks of intervention for the 4-h TRF, 6-h TRF and Ad lib control group.
Values reported as mean ± SEM. Data were included for 58 participants; means were estimated by an intention-to-treat analysis using last observation carried forward. Each data point represents an individual participant. Mean change is indicated by a black data point. *P < 0.05, change score between baseline to week 8 by ANCOVA.