Table 1.

Range of intrinsic parameter values for TFs and non-TF genes

Parameter	Interquartile ranges	Refs.
Time between bursts (1/kON)		67, 70
Burst duration (1/kOFF)		67, 70
mRNA half-life		65, 69, 81
Protein half-life		69
Burst size		55, 67, 74
Translation rate		65, 69

Derived from literature, where parameters were estimated and inferred from published experimental data. Lines represent first quartile, median, and third quartile values for TFs (blue) and non-TFs (red), respectively. Burst sizes used in simulations were based on previously published smFISH-based copy numbers, although we note that scRNA-seq data-based estimates are lower due to transcript capture inefficiencies (88–90). k_on = burst frequency; k_off = number of burst ends per hour.