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. 2022 Aug 19;13(8):1484. doi: 10.3390/genes13081484

Table 3.

Prognostic factors for overall survival in univariable and multivariable analyses.

Factor Univariable Analysis Multivariable Analysis
Hazard Ratio (95% CI) p-Value Hazard Ratio (95% CI) p-Value
Hsa_circ_0003570 (high expression) 0.515 (0.331–0.801) 0.003 * 0.541 (0.327–0.894) 0.017 *
Age (>60 years) 1.100 (0.711–1.701) 0.669 1.397 (0.820–2.381) 0.219
Sex (male) 1.097 (0.594–2.026) 0.766 1.368 (0.679–2.756) 0.381
Tumor number (multiple) 2.408 (1.549–3.743) <0.001 * 0.825 (0.463–1.470) 0.514
AFP (>200 ng/mL) 2.938 (1.885–4.579) <0.001 * 1.457 (0.871–2.438) 0.152
CTP classification (B vs. A) 3.259 (1.881–5.648) <0.001 * 2.271 (1.122–4.595) 0.023 *
Chronic hepatitis B 0.594 (0.383–0.922) 0.020 * 0.809 (0.486–1.347) 0.415
Curative treatment 0.141 (0.086–0.231) <0.001 * 0.171 (0.090–0.325) <0.001 *

CI—confidence interval; AFP—α-fetoprotein; CTP—Child–Turcotte–Pugh. * p < 0.05.