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. 2022 Aug 19;13(8):1484. doi: 10.3390/genes13081484

Table 4.

Prognostic factors for progression-free survival in univariable and multivariable analyses.

Factor Univariable Analysis Multivariable Analysis
Hazard Ratio (95% CI) p-Value Hazard Ratio (95% CI) p-Value
Hsa_circ_0003570 (high expression) 0.580 (0.388–0.867) 0.008 * 0.633 (0.402–0.997) 0.048 *
Age (>60 years) 0.887 (0.600–1.311) 0.548 0.919 (0.575–1.467) 0.723
Sex (Male) 1.216 (0.713–2.076) 0.473 1.719 (0.945–3.125) 0.076
Tumor number (multiple) 1.950 (1.316–2.889) 0.001 * 0.754 (0.455–1.248) 0.272
AFP (>200 ng/mL) 2.767 (1.845–4.148) <0.001 * 1.569 (0.963–2.557) 0.070
CTP classification (B vs. A) 2.869 (1.676–4.911) <0.001 * 2.163 (1.098–4.261) 0.026 *
Chronic hepatitis B 0.766 (0.514–1.141) 0.190 0.967 (0.614–1.526) 0.887
Curative treatment 0.186 (0.120–0.288) <0.001 * 0.235 (0.133–0.416) <0.001 *

CI—confidence interval; AFP—α-fetoprotein; CTP—Child–Turcotte–Pugh. * p < 0.05.