Table 2.
Identified mutation in exons 18–21 of the EGFR in Tunisian NSCLC patients. *: Deceased before starting the target therapy.
| Patient | Gender | Age | EGFR Alteration | Metastasis | Smoking History | Therapy | Status | Survival (Months) |
|---|---|---|---|---|---|---|---|---|
| P3 | M | 60 | p.L861Q | Lymph nodes | 30 PA | Chemotherapy | dead | 37 |
| P4 | M | 46 | p.T790M | Liver, Bones | 20 PA | - | - | - |
| P27 | F | 65 | p.L861Q | Lung | No | Chemotherapy + Erlotinib | alive | 40 |
| P34 | M | 72 | p.L861R | No | 25 PA | Chemotherapy | dead | 18 |
| P35 | M | - | p.L861R | No | 30 PA | - | - | - |
| P36 | M | 50 | p.E746_A750del/p.L861R | Bones | 40 PA | Erlotinib | alive | 15 |
| P37 | M | 60 | p.G719S | Brain | No | Chemotherapy | dead | 35 |
| P40 | M | 72 | p.G719A | Lung | No | - | - | - |
| P42 | M | 63 | p.E746_A750del | Bones | 60 PA | Chemotherapy | alive | 17 |
| P104 | M | - | p.L861Q | - | 20 PA | - | - | - |
| P105 | M | - | p.E746_A750del | Liver | 40 PA | - | - | - |
| P106 | F | - | p.E746_S752>V/p.S768I | Bones | No | - | - | - |
| P109 | F | - | p.E746_T751>I | Bones | 10 PA | - | - | - |
| P112 | M | - | p.L861R | Brain | 50 PA | - | - | - |
| P117 | F | - | p.L747_T751del | Bones | 15 PA | - | - | - |
| P120 | M | 66 | p.G719A/p. L861Q | Liver | No | - | - | - |
| P121 | M | 51 | p.L858R | Lung | No | - | - | - |
| P125 | M | 54 | p.E746_A750del | Lung | 30 PA | - | - | - |
| P128 | M | p.L858R | Liver | No | - | - | - | |
| P134 | M | 67 | p.L861Q | No | No | - | - | - |
| P135 | M | 54 | p.G719C | No | 40 PA | - | - | - |
| P136 | M | 76 | p.E746_A750del | No | 20 PA | Surgery | alive | 7 |
| P137 | F | 63 | p. L861Q | No | No | - | - | |
| P139 | M | 64 | p. G719C | Adrenal | 40 PA | Chemotherapy | alive | 18 |
| P140 | M | 66 | p. L861Q | Bones | Unknown | Chemotherapy + Erlotinib | dead | 1 |
| P145 | M | 59 | p.L858R | No | 50 PA | * | dead | 3 |
| P146 | F | 48 | p.G719A | Bones | No | * | dead | 4 |
| P148 | F | 70 | p. L861Q | No | No | - | - | - |
| P149 | F | 60 | p. L861R | No | No | Erlotinib | alive | 3 |
| P150 | M | 62 | p. L861Q | No | No | - | - | - |
| P156 | M | 62 | p. L861Q | Liver | 40 PA | - | - | - |
| P157 | M | 54 | p. L861Q | Liver | No | Erlotinib | alive | 2 |
| P158 | M | 56 | p. L861Q | Liver | 30 PA | - | - | - |
| P160 | F | 75 | p. L858R | Bones | No | Erlotinib | alive | 2 |