Table 5.
Parameter | IPI Score | MIR-34A | MIR-34B/C | MIR-203 | MIR-129-2 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
0–2 | 3–5 | p-Value | M | U | p-Value | M | U | p-Value | M | U | p-Value | M | U | p-Value | |
Remission rate Abs (%) |
24/29 | 28/44 | 0.078 | 11/20 (55) |
41/53 (77.4) |
0.060 | 33/45 | 19/28 | 0.616 | 35/48 | 17/25 | 0.660 | 36/49 | 16/24 | 0.547 |
OS (%) | 65.5 | 43.2 | 0.043 | 40.0 | 56.6 | 0.162 | 53.3 | 50.0 | 0.699 | 54.2 | 48.0 | 0.590 | 57.1 | 41.7 | 0.269 |
Keys: M—methylated, U—unmethylated, OS—overall survival.