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. 2022 Aug 9;23(16):8852. doi: 10.3390/ijms23168852

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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A representative trace of HRR in permeabilized cells (platelets) displaying the oxygen concentration in the chamber over time (blue trace) and the oxygen flux (red trace) according to the SUIT protocol. The additions are provided in the upper part of the chart. The respiratory parameters are provided in the lower part: ROUTINE respiration; OXPHOS capacity (the maximal active respiration in the presence of CI and CII substrates plus ADP); LEAK (the non-phosphorylating respiration in the presence of oligomycin); ET capacity (the maximal uncoupled respiration in the presence of FCCP); and ROX (residual oxygen consumption). See the explanations in the text above.