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. 2022 Aug 9;23(16):8852. doi: 10.3390/ijms23168852

Table 4.

High-resolution respirometry findings in human obesity studies.

Cell Type
(Harvest Site)		 Main Effects Normalization Ref.
Skeletal muscle
(vastus lateralis)		 Reduced NADH-linked OXPHOS
Reduced OXPHOS capacity
Reduced ET-capacity		 Tissue mass [75]
Skeletal muscle
(deltoideus;
vastus lateralis)		 No change in NADH-linked OXPHOS
No change in OXPHOS capacity
No changes in ROX		 Tissue mass [76]
Skeletal muscle
(quadriceps femoris)		 Decreased OXPHOS capacity
No change in ET capacity		 Tissue mass [74]
Liver tissue
(lower part of right liver lobe)		 Increased NADH-linked OXPHOS
Increased OXPHOS capacity
Increased ET-capacity
Decreased RCR
Increased L/E coupling control ratio 		Tissue protein [82]
Liver tissue
(lower part of right liver lobe)		 No change in NADH-linked OXPHOS
No change in succinate linked OXPHOS
No change in ET-capacity		 Tissue mass [81]
Adipose tissue
(abdominal subcutaneous;
intra-abdominal visceral from omentum majus)		 No change in RCR
Decreased UCR
Visceral fat vs. subcutaneous fat		 Number of cells
mtDNA content		 [83]
Myometrial biopsies No change in NADH-linked OXPHOS
No change in OXPHOS capacity
Decreased RCR		 No information [86]