Table 2.
Genetic association models (dominant, recessive and homozygote vs. heterozygote) of IRS-1 Gly972Arg polymorphism in PCOS and controls.
| Comparison | PCOS N/n (%) |
Control N/n (%) |
Odds Ratio (95% CI) |
χ2 | p Value |
|---|---|---|---|---|---|
| GG + GA vs. AA | 241/8 (96.78% vs. 3.21%) |
98/2 98% vs. 2%) |
1.63 (0.34–7.80) |
0.37 | 0.53 |
| GG vs. GA + AA | 154/95 (61.84% vs. 31.15%) |
56/44 (56% vs. 44%) |
0.79 (0.49–1.26) |
1.01 | 0.31 |
| GA vs. GG + AA | 87/162 (34.93% vs. 65.06%) |
42/58 (42% vs. 58%) |
1.34 (0.83–2.16) |
1.53 | 0.22 |
N/n: numbers in genotype compared, CI: confidence interval. χ2: Pearson chi-squared test.