Table 3.
Comparison of anthropometric, hormonal, metabolic and biochemical parameters in PCOS cases and healthy controls.
| Parameter | PCOS (n = 249) | Controls (n = 100) | p Value |
|---|---|---|---|
| Age (years) | 22.43 ± 4.14 | 22.01 ± 3.17 | 0.36 |
| Weight (kg) | 59.83 ± 11.59 | 51.94 ± 6.72 | <0.001 * |
| Height (m) | 1.57 ± 0.05 | 1.57 ± 0.05 | 0.51 |
| BMI (kg/m2) | 24.28 ± 4.69 | 21.16 ± 2.48 | <0.001 * |
| BAI | 29.58 ± 4.73 | 28.62 ± 3.04 | 0.061 |
| Waist (cm) | 83.10 ± 11.13 | 77.01 ± 7.11 | <0.001 * |
| Hip (cm) | 93.47 ± 8.24 | 91.30 ± 6.33 | 0.018 * |
| WHR | 0.89 ± 0.08 | 0.84 ± 0.06 | <0.001 * |
| SBP (mmHg) | 120.58 ± 7.51 | 118.96 ± 5.40 | 0.05 |
| DBP (mmHg) | 80.54 ± 5.89 | 79.32 ± 5.23 | 0.072 |
| Menarche (years) | 13.14 ± 1.14 | 13.28 ± 1.07 | 0.29 |
| FG score | 13.95 ± 6.58 | 4.53 ± 1.84 | <0.001 * |
| LH (IU/L) | 11.29 ± 9.54 | 6.65 ± 2.35 | <0.001 * |
| FSH (IU/L) | 6.09 ± 1.87 | 6.90 ± 1.97 | <0.001 * |
| TT (ng/dL) | 61.04 ± 23.93 | 34.15 ± 15.60 | <0.001 * |
| PRL (ng/mL) | 13.29 ± 5.61 | 10.42 ± 4.93 | <0.001 * |
| TSH (μIU/L) | 3.18 ± 1.44 | 2.99 ± 1.47 | 0.268 |
| SHBG (nmol/L) | 50.07 ± 21.67 | 64.91 ± 25.42 | <0.001 * |
| Andro (ng/mL) | 3.26 ± 0.86 | 2.26 ± 0.69 | <0.001 * |
| DHEAS (ng/mL) | 3.79 ± 1.15 | 2.9 ± 1.3 | <0.001 * |
| Insulin F (μIU/mL) | 13.53 ± 7.19 | 7.72 ± 5.39 | <0.001 * |
| Glu F (mg/dL) | 85.70 ± 8.59 | 84.54 ± 8.87 | 0.20 |
| Glu 2 h (mg/dL) | 115.47 ± 18.01 | 108.55 ± 14.29 | <0.001 * |
| Chol (mg/dL) | 154.73 ± 34.64 | 135.11 ± 19.30 | <0.001 * |
| TG (mg/dL) | 120.59 ± 35.57 | 102.73 ± 14.78 | <0.001 * |
| HOMA IR | 2.83 ± 1.68 | 1.62 ± 1.36 | <0.001 * |
| QUICKI | 0.338 ± 0.02 | 0.38 ± 0.05 | <0.001 * |
| FAI | 5.77 ± 5.62 | 2.21 ± 1.66 | <0.001 * |
| LH/FSH | 1.91 ± 1.27 | 1.04 ± 0.54 | <0.001 * |
| LAP | 35.16 ± 21.81 | 22.20 ± 9.08 | <0.001 * |
| Urea (mg/dL) | 22.76 ± 5.97 | 21.32 ± 3.47 | 0.024 * |
| UA (mg/dL) | 4.27 ± 1.09 | 3.84 ± 0.75 | <0.001 * |
| Creatinine (mg/dL) | 1.03 ± 0.43 | 0.80 ± 0.13 | <0.001 * |
| AST (U/L) | 31.39 ± 12.46 | 18.30 ± 7.84 | <0.001 * |
| ALT (U/L) | 27.84 ± 13.82 | 23.46 ± 6.78 | 0.002 * |
Data presented as mean ± SD, * p value < 0.05 was considered significant calculated by Student’s t-test. y: years, BMI: body mass index, WHR: waist–hip ratio, WHtR: waist to height ratio, FG score: Ferriman–Gallwey score, SBP: systolic blood pressure, DBP: diastolic blood pressure, LH: luteinizing hormone, FSH: follicle-stimulating hormone, TSH: thyroid-stimulating hormone, SHBG: sex hormone-binding globulin, DHEAS: dihydroepiandrosterone sulphate, FAI: free androgen index, BAI: body adiposity index, LAP: lipid accumulation product, AST: aspartate aminotransferase, ALT: alanine aminotransferase.