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. 2022 Aug 17;13(8):1463. doi: 10.3390/genes13081463

Table 6.

Comparison of the present study with previous studies of IRS-1 gene Gly972Arg polymorphism in PCOS.

Author Year Ethnicity/Population Case/Controls p Value
ElMkadem et al., 2001 [14] 2001 Caucasian/French 53/102 0.39
Sir-Petermann et al., 2004 [16] 2004 Caucasian/Chilean 143/97 0.10
Haap et al., 2005 [37] 2005 Caucasian/German 56/316 0.53
Villuendas et al., 2005 [34] 2005 Caucasian/Spanish 103/48 0.74
Dilek et al., 2005 [39] 2005 Caucasian/Turkish 60/60 0.03 *
Lin et al., 2006 [32] 2006 Asian/Taiwanese 47/45 NS
Valdés et al., 2008 [19] 2008 Caucasian/Chilean 50/75 0.18
Baba et al., 2007 [40] 2007 Asian/Japanese 123/380 0.014 *
Pappalardo et al., 2010 [41] 2010 Caucasian/Italian 65/27 <0.001 *
Skrgatic et al., 2013 [36] 2013 Caucasian/Croatian 150/170 0.25
Marioli et al., 2010 [29] 2010 Caucasian/Greek 162/122 0.81
Lin et al., 2014 [42] 2014 Asian/Taiwanese 248/92 0.50
Dasgupta et al., 2012 [30] 2012 South Asian/Indian 246/279 0.67
Oh et al., 2009 [31] 2009 Asian/Korean 125/344 >0.05
Shi et al., 2016 [21] 2016 Meta-analysis 1851/2017 0.004 *
Thangavelu et al., 2017 [18] 2017 South Asian/Indian 169/169 0.001 *
Pappalardo et al., 2016 [20] 2016 Caucasian/Italian 100/45 0.008 *
Christopoulos et al., 2010 [38] 2010 Caucasian/Greek 183/88 0.002 *
Present study 2022 South Asian/Kashmiri 249/100 0.49

* p Value of the study < 0.05.