Technology advances could be useful to support clinicians in their activity thanks to the application of digital devices for telemedicine or tech-based intervention for monitoring, prevention, education, and clinical management of delirium. The importance of technology application comes from the lack of biomarkers for delirium diagnosis, and this determines the underestimation and undertreatment of this impacting syndrome. Technology sprouting will guarantee overcoming logistic obstacles to an aging-friendly environment realization in the healthcare setting, reducing the stress of healthcare workers when they deal with patients developing delirium.