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. 2022 Jul 28;10(8):1413. doi: 10.3390/healthcare10081413

Table 1.

Summary of commercially available anti-erosive agents in the literature.

Agents Concentration of Active Ingredients Delivery
System
Example of Product Names
and Companies
NaF 1100 ppm F of NaF Toothpaste
  • Colgate® Total®, Colgate-Palmolive [33,43]

  • Crest® Cavity Protection, The Procter & Gamble [44]

1450 ppm F of NaF Toothpaste
  • SensodyneTM ProNamel®, GSK [18,19,21]

  • Crest® Decay Protection, The Procter & Gamble [41]

  • Colgate® Total®, Colgate-Palmolive [46]

5000 ppm F of NaF Toothpaste
  • Prevident 5000®, Colgate–Palmolive [20]

AmF + SnCl2 800 ppm Sn SnCl2 + 500 ppmF of NaF+ AmF Mouthrinse
  • Elmex® Erosion Protection dental rinse, GABA Schweiz, Colgate-Palmolive [12,50]

AmF + SnF2 250 ppm F of AmF + SnF2 Mouthrinse
  • Meridol®, Colgate-Palmolive [34]

1450 ppmF of AmF + SnF2 Toothpaste
  • Meridol®, GABA Benelux [35]

SnF2 0.4–0.454% SnF2, 1100–1450 ppm F of SnF2 Toothpaste
  • Crest® Pro HealthTM Advanced Gum Protection, The Procter & Gamble [33,42,43]

  • Solidox, Lilleborg [51]

1450 ppm F of NaF + SnF2 Toothpaste
  • Oral-B® Pro-Expert Sensitive; The Procter & Gamble [21,47]

CPP-ACP 10% CPP-ACP Gum
  • Trident Total®/Recaldent®, Trident [74]

10% CPP-ACP Cream
  • GC Tooth Mousse, GC Company [73,75,81]

  • MI Paste, GC company [80]

10% CPP-ACP with 900 ppm F of NaF Cream
  • GC Tooth Mousse Plus, GC Company [81]

  • MI Paste Plus, GC company [75,80]

2% CPP-ACP + 22,600 ppm F of NaF Varnish
  • MI varnish, GC Company [13]

CSSP CSSP with 1450 ppm F of SMFP Toothpaste
  • RegenerateTM Enamel Science, Unilever Oral Care [83,86]

β-TCP 5% TCP + 22,600 ppm F of NaF Varnish
  • Clinpro white varnish, 3M ESPE [13]

n-HAP 2.25–20% n-HAP Toothpaste
  • Biorepair Sensitive Repair, Coswell [95]

  • PrevDent, PrevDent International [90]

1% n-HAP + 1450 ppm F of NaF Toothpaste
  • ApaCare, Cumdente [90]

Arginine 1.5% Arginine + 1450 ppm F of SMFP Toothpaste ∙ Colgate® Maximum Cavity Protection, Colgate-Palmolive [115,117]
8% Arginine + 1450 ppm F of SMFP Toothpaste
  • Colgate Sensitive Pro-Relief®, Colgate-Palmolive [114,118]

Chitosan 0.5% Chitosan + 1400 ppm F AmF/NaF + 3500 ppm Sn SnCl2 Toothpaste
  • Elmex® Erosionschutz and Elmex® Erosion Protection, GABA Schweiz, Colgate-Palmolive [47]

CHX 0.2% Chlorhexidine Mouthrinse
  • Periogard, Colgate-Palmolive [159]

  • Klorhex, Drogsan Pharmaceutical [161]

NaF, sodium fluoride; SnF2, stannous fluoride; AmF, amine fluoride; SnCl2, stannous chloride; CPP-ACP, casein phosphopeptide amorphous calcium phosphate; CPP-ACFP, casein phosphopeptide amorphous calcium fluoride phosphate; CSSP, calcium silicate and sodium phosphate; β-TCP, β-tricalcium phosphate; F, fluoride; SMFP, sodium monofluorophosphate; ppm, parts per million; n-HAP, nano hydroxyapatite; CHX, chlorhexidine.