Table 1.

Molecular docking analysis of the ligands caffeic acid, chlorogenic acid and kynurenic acid with target TOP1.

Compound-Protein	Interacting Amino Acid Residues	Final Intermolecular Energy
Caffeic acid	GLY496, GLU494, THR498, LYS493, THR501, VAL502	−6.1 kcal/mol
Chlorogenic acid	LYS284, GLU285, LEU373, ILE420, ASN419, THR417	−6.4 kcal/mol
Kynurenic acid	PRO229, AGR376	−6.6 kcal/mol

The table shows the list of interacting amino acids and binding energy.