Table 3.
Frequency of genotypes of the DRD2 rs6276 gene polymorphisms estimated in SUD patients with mania SUD MANIA, patients with only SUD and without mania, and healthy controls.
| Group | DRD2 rs6276 | ||||
|---|---|---|---|---|---|
| Genotypes | Alleles | ||||
| A/A n (%) |
A/G n (%) |
G/G n (%) |
A n (%) |
G n (%) |
|
| A: SUD MANIA n = 89 |
42 (47.2) |
37 (41.6) |
10 (11.2) |
121 (68.0) |
57 (32.0) |
| B: SUD n = 195 |
85 (43.6) |
89 (45.6) |
21 (10.8) |
259 (66.4) |
131 (33.6) |
| C: Control n = 301 |
127 (42.2) |
129 (42.9) |
45 (15.0) |
383 (63.6) |
219 (36.45) |
| χ2 (p value) | A/B: 0.71 (0.701) A/C: 1.09 (0.578) B/C: 1.82 (0.403) |
A/B: 0.14 (0.713) A/C: 1.14 (0.286) B/C: 0.81 (0.369) |
|||
n—number of subjects.