Table 5.

Differences in DRD2 rs6276 and NEO Five-Factor Inventory, STAI scale between healthy control subjects and SUD and SUD MANIA.

STAI/NEO Five-Factor Inventory	Group	DRD2 rs6276			ANOVA
		A/A n = 251	A/G n = 260	G/G n = 80	F (p-Value)	η2	Power (Alfa = 0.05)
STAI trait/scale	SUD MANIA; n = 95	7.71 ± 2.21	7.64 ± 2.61	6.40 ± 1.07	F4,589 = 1.379 (p = 0.2397)	0.009	0.431
	B: SUD; n = 195	6.87 ± 2.28	6.80 ± 2.25	7.60 ± 2.04
	C: Control; n = 301	5.26 ± 2.21	5.07 ± 2.03	5.16 ± 2.51
STAI state/scale	SUD MANIA; n= 95	6.38 ± 2.41	6.03 ± 2.58	6.80 ± 0.63	F4,589 = 0.963 (p = 0.4274)	0.006	0.306
	B: SUD; n = 195	5.61 ± 2.48	5.70 ± 2.50	6.32 ± 1.97
	C: Control; n = 301	4.97 ± 2.18	4.45 ± 2.00	4.58 ± 2.36
Neuroticism/scale	SUD MANIA; n= 95	7.29 ± 1.91	7.05 ± 2.27	5.80 ± 1.23	F4,589 = 2.659 (p = 0.0320 *)	0.017	0.742
	B: SUD; n = 195	6.32 ± 2.15	6.628 ± 2.30	7.48 ± 2.02
	C: Control; n = 301	4.75 ± 2.07	4.65 ± 1.93	4.49 ± 2.11
Extraversion/scale	SUD MANIA; n= 95	5.83 ± 2.27	6.19 ± 2.62	5.60 ± 1.51	F2,389 = 1.434 (p = 0.2213)	0.010	0.447
	B: SUD; n = 195	6.02 ± 2.02	5.52 ± 1.95	5.08 ± 2.33
	C: Control; n = 301	6.67 ± 1.99	6.05 ± 2.00	6.47 ± 1.75
Openness/scale	SUD MANIA; n= 95	5.48 ± 2.09	5.27 ± 2.49	4.70 ± 1.34	F2,389 = 0.231 (p = 0.9208)	0.002	0.100
	B: SUD; n = 195	4.86 ± 1.84	4.99 ± 2.06	4.56 ± 1.85
	C: Control; n = 301	4.51 ± 1.72	4.63 ± 1.46	4.31 ± 1.68
Agreeability/scale	SUD MANIA; n= 95	4.42 ± 2.15	3.54 ± 1.83	5.20 ± 1.87	F2,389 = 1.221 (p = 0.3008)	0.008	0.384
	B: SUD; n = 195	4.32 ± 1.66	4.35 ± 1.98	4.56 ± 2.18
	C: Control; n = 301	5.51 ± 2.22	5.50 ± 1.94	6.13 ± 2.06
Conscientiousness/scale	SUD MANIA; n= 95	4.90 ± 2.22	5.38 ± 2.24	5.20 ± 2.35	F2,389 = 0.558 (p = 0.6933)	0.004	0.186
	B: SUD; n = 195	5.66 ± 2.37	5.92 ± 2.32	5.68 ± 1.75
	C: Control; n = 301	6.19 ± 2.27	5.96 ± 2.10	6.11 ± 1.92

*—significant result.