Table 1.
Number of different ovarian follicles and corpora lutea of immature female Wistar rats after 40 days of treatment.
| Organs | Control | Tartrazine (mg/kg BW) | ||
|---|---|---|---|---|
| T 7.5 | T 27 | T 47 | ||
| Total follicles | 92.98 ± 11.90 | 99.38 ± 11.80 | 83.49 ± 13.74 | 145.33 ± 2.37 ** |
| Primordial follicles | 35.33± 7.83 | 28.00 ± 5.42 | 21.33 ± 3.59 | 38.00 ± 3.83 |
| Primary follicles | 22.00 ± 2.60 | 20.33 ± 2.93 | 18.66 ± 3.00 | 37.50 ± 2.53 ** |
| Secondary follicles | 16.50 ± 1.20 | 30.40 ± 5.76 | 28.25 ± 8.29 | 44.25 ± 2.37 ** |
| Antral follicles | 4.20 ± 0.96 | 6.25 ± 1.23 | 4.80 ± 1.59 | 10.33± 1.42 * |
| Graafian follicles | 5.00 ± 1.04 | 6.80 ± 0.8 | 4.80 ± 1.01 | 6.50 ± 0.92 |
| Atresia follicles | 4.75 ± 0.19 | 3.80 ± 0.66 | 3.25 ± 0.58 | 3.75 ± 0.91 |
| Corpora lutea | 5.20 ± 1.20 | 3.80 ± 1.11 | 2.40 ± 0.60 | 5.00 ± 0.83 |
Results are presented as mean ± SEM; (*: p < 0.05), (**: p < 0.01) in reference to control. Control = animals receiving vehicle (distilled water, 10 mL/kg BW); T = rats treated with tartrazine at doses of 7.5; 27, and 47 mg/kg BW.