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. 2022 Aug 9;23(16):8869. doi: 10.3390/ijms23168869

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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DAPT treatment reduced the expression of genes related to the cell cycle and DNA replication. (A) Heatmap of differential expressed genes in cell cycle pathway (n = 3). (B) Heatmap of differentially expressed genes in the DNA replication pathway (n = 3). (C) The mRNA expression levels of selected genes were determined by qRT-PCR (n = 4). Bars represent a significant difference between groups (p < 0.05).