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. 2022 Aug 19;23(16):9332. doi: 10.3390/ijms23169332

Table 2.

The basic clinical and laboratory parameters of patients with positive results of a plasma rtPCR test for TBEV RNA.

No. Sex Age Comorbidities Presentation 1 Phase 2 Main Symptoms 2 Time Since Onset 2 Anti-TBEV IgM in Serum 2 TBEV RNA
in Plasma
(ct Value)		 TBEV RNA
in Whole Blood
(ct Value)		 TBEV RNA
in CSF 2 		Follow Up TBEV RNA
1 M 68 hypertension, hyperuricaemia, Lyme borreliosis MEM neurologic headache,
vertigo,
neck stiffness,
flaccid paresis		 19 days;
neurologic phase—8 days		 negative 30.6 32.0 negative ND
2 F 51 none meningitis peripheral fever,
arthralgia,
headache		 5 days negative 32.6 negative ND negative plasma and CSF on day 17
(6th day of the neurologic phase)
3 F 59 possible Lyme borreliosis meningitis peripheral fever,
headache,
maculopapular rash		 4 days negative 32.5 negative negative ND
4 F 31 none abortive infection peripheral headache,
myalgia,
nausea,
neck stiffness		 3 days negative 35.2 negative negative ND

1 Final diagnosis on discharge. 2 At the time of the TBEV RNA-positive plasma sample collection. M—male; F—female; MEM—meningoencephalomyelitis; ND—not done.