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. 2022 Aug 15;23(16):9163. doi: 10.3390/ijms23169163

Table 2.

The inhibition effectiveness of Compound 4 and 6 by inhibitory potency (IC50) and affinity strength (Ki) of Bla2.

IC50 (μM) Ki (μM)
Compound 4 20.0 ± 5.0 6.4 ± 1.7
Compound 6 14.9 ± 9.8 4.7 ± 1.4
SAHA >100 N.D. *

* Data were not determined due to the high IC50 value.