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. 2022 Aug 15;23(16):9159. doi: 10.3390/ijms23169159

Table 1.

Potentially preventive strategies for SA-AKI.

Strategies Remarks
Prompt and proper antibiotics administration Treatment of infection and sepsis
Vasopressor keeping a mean arterial blood pressure > 65 mmHg (norepinephrine preferred) Maintain renal perfusion and autoregulation
Balanced crystalloid fluid administration Avoidance of chloride overload. With benefit on major kidney adverse events
Avoidance of nephrotoxic agents e.g., some antibiotics and contrast media
Application of the KDIGO bundle (?) Effects under evaluation
High awareness of abdominal compartment syndrome High intra- abdominal pressure is a deteriorating factor of SA-AKI

Abbreviations: SA-AKI, sepsis-associated acute kidney injury; KDIGO, Kidney Disease Improving Global Outcomes.