Table 1.
Strategies | Remarks |
---|---|
Prompt and proper antibiotics administration | Treatment of infection and sepsis |
Vasopressor keeping a mean arterial blood pressure > 65 mmHg (norepinephrine preferred) | Maintain renal perfusion and autoregulation |
Balanced crystalloid fluid administration | Avoidance of chloride overload. With benefit on major kidney adverse events |
Avoidance of nephrotoxic agents | e.g., some antibiotics and contrast media |
Application of the KDIGO bundle (?) | Effects under evaluation |
High awareness of abdominal compartment syndrome | High intra- abdominal pressure is a deteriorating factor of SA-AKI |
Abbreviations: SA-AKI, sepsis-associated acute kidney injury; KDIGO, Kidney Disease Improving Global Outcomes.