Table 5.

Nonparametric correlation between the studied parameters, the Breslow thickness, Clark level, and the melanoma stage.

		Trp	Kyn	KYNA	5-HIAA	DHICA	IS
Kyn	rho	0.474 **
	p-value	8.17 × 10−9
KYNA	rho	0.728 **	0.541 **
	p-value	3.36 × 10−23	1.73 × 10−11
5-HIAA	rho	0.688 **	0.578 **	0.69 1**
	p-value	7.94 × 10−19	1.76 × 10−12	4.69 × 10−19
DHICA	rho	0.689 **	0.470 **	0.702 **	0.646 **
	p-value	1.35 × 10−18	4.10 × 10−8	1.50 × 10−19	1.20 × 10−15
IS	rho	0.741 **	0.569 **	0.809 **	0.675 **	0.783 **
	p-value	1.97 × 10−24	9.36 × 10−13	4.83 × 10−32	5.79 × 10−18	1.03 × 10−26
Breslow thickness	rho	−0.130	0.028	−0.064	−0.246	−0.361 **	−0.136
	p-value	0.285	0.821	0.601	0.054	0.005	0.261
Clark level	rho	0.069	0.143	0.079	−0.139	−0.184	−0.007
	p-value	0.568	0.235	0.513	0.276	0.155	0.953
Melanoma stage	rho	−0.151	0.030	−0.165	−0.320 **	−0.491 **	−0.229 *
	p-value	0.177	0.789	0.137	0.005	1.19 × 10−5	0.038

Trp—tryptophan in µmol/mmol of creatinine; Kyn—kynurenine in µmol/mmol of creatinine; KYNA—kynurenic acid in µmol/mmol of creatinine; DHICA—5,6-dihydroxyindole-2-carboxylic acid in µmol/mmol of creatinine; IS—indoxyl sulfate in µmol/mmol of creatinine; 5-HIAA—5-hydroxyindole-3-acetic acid in µmol/mmol of creatinine; rho—Spearman’s rho correlation coefficient; significance 2-tailed; *—correlation is significant at the 0.005 level; **—correlation is significant at the 0.010 level.