Table 3.
Proteins identified by MALDI-TOF/TOF corresponding to those spots present in >70% of the AIEC strains and absent in the commensal E. coli HS strain.
| Function | No. Spot |
Protein | Description | E-Value |
|---|---|---|---|---|
| Iron uptake | 1 | ChuA | Hemo/iron group receptor | 1.58114 × 1092 |
| 2 | CirA | Siderophore, colicin, microcin receptor | 1.25594 × 1036 | |
| 3 | FitA | Iron-ferrichrome receptor | 1.25594 × 1079 | |
| 4,5 | FepA | Ferrienterobactin receptor | 5 × 1050 6.29463 × 1055 |
|
| 6 | Lgc * | Ligand-regulated channel (potential iron receptor) | 3.97164 × 1021 | |
| 18 | IrpC | Yersiniabactin/pesticin receptor | 1.58114 × 1054 3.15479 × 1036 |
|
| Porins | 10 | OmpT | Protease, outer membrane protein | 6.29463 × 1044 |
| 8 | NmpC | Outer membrane protein | 3.15479 × 1077 | |
| 21,22 | OmpA | Outer membrane protein | 7.92447 × 1061 1.25594 × 1067 |
|
| 13 | EefC/NodT | Outer membrane channel | 3.97164 × 1056 | |
| 14,15 | TolC | Outer membrane protein | 3.15479 × 1020 | |
| Specific channel | 16,17 | BtuB | B12 vitamin transporter | 3.15479 × 1017 |
| Stress response | 19,20 | Dps | DNA-protecting protein | 9.97631 × 1072 8.34568 × 1060 |
| Others | 11,12 | LptD | LPS-assembly protein | 9.97631 × 1053 3.15479 × 105 |
| 7 | Tsx | Nucleoside receptor, phage T6 and colicin K receptor | 1.58114 × 1028 | |
| 9 | EF-Tu | Elongation factor Tu | 3.15479 × 1023 |
* Abbreviation proposed in this work to refer to a certain protein.