Table 1.
Table summarizing the influence of different types of therapy on AD patients.
| Type of Therapy | Influence | Author | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cognitive Functions | Attention | Learning | Memory | Aβ Plaques | Agitation | Proinflammatory Response | Progression of AD | Emotions | Side Effects | ||
| Cholinesterase inhibitors | ↑ | ↑ | ↑ | ↑ | insomnia, gastrointestinal symptoms (nausea, loss of appetite, diarrhea), muscle cramping and weakness | [31,32,33,34] | |||||
| Memantine | ↑ | ↑ | ↑ | Confusion, aniety | [42,43,44,45] | ||||||
| Aducanumab | ↑ | Removal, disturbing accumulation | micro-bleeds, swelling in the brain, dizziness, headaches nausea | [49] | |||||||
| Antidepressants | ↓ | ↑ | Citalopram: risk of QT prolongation | [62,63] | |||||||
| Vitamin E | ↑ | Overdosage: fatigue, gastrointestinal cramps, diarrhea | [72] | ||||||||
| Melatonin | Prevent accumulation | ↓ | ND | [83,85,86] | |||||||
| Curcumin | ↑ | Prevent accumulation | ND | [89,94,95] | |||||||
| Ginkgo biloba | ↑ | ↓ | ND | [102] | |||||||
| Saffron | ↑ | ↑ | ↑ | ND | [109,110] | ||||||
| Ashwaganda | ↓toxicity | ND | [118] | ||||||||
| Physical activities | ↑ | ND | [124,125] | ||||||||
| Social activities | ↑ | ND | [144,148] | ||||||||
| Music therapy | ↑ | ↑ | ↑ | ND | [151,153] | ||||||
| Anti-inflammatory treatment | ↑ | ↓pathology | ND | [157,158,160] | |||||||
| Gut microbiota alterations | Stopping development | ND | [177] | ||||||||
ND—Not described.