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SDS-PAGE analysis of H4 histone hydrolysis by IgG-abzymes against five histones (A) and this histone with IgGs against MBP (B) as well as splitting myelin basic protein by IgGs against five histones (C) and IgG-abzymes against MBP (D). Lanes C correspond to the histones (A) and MBP (B) incubated without IgGs. MBP and a mixture of five histones with and without IgGs (0.03 mg/mL) were incubated for 12 h.
