Table 7.

miRNAs involved in sepsis-induced brain dysfunction and their target. ↑ indicates up regulation, ↓ indicates down regulation.

miRNA	Target Gene/Pathway	Upregulation/Downregulation and Its Effect on Brain Function	Author and Reference
miR-181b	-	↓miR-181b ↓Brain function	Dong et al. [19]
miR-200a-3p	NLRP3	↑miR-200a-3p ↑NLRP3 ↓Brain function	Yu et al. [21]
miR-181b	S1PR1 NCALD	↑miR-181b ↓S1PR1 and NCALD ↓Brain function	Chen et al. [20]
miR-370-3p	-	↑ miR-370-3p ↓Brain function	Visitchanakun et al. [22]
miR-147	-	↓ miR-147 ↓Brain function	Kim et al. [23]
miR-126	-	↓miR-126 - ↓Brain function	Nong et al. [24]
miR-190a-3p, miR-3085-3p	-	↑ miR-190a-3p, ↓miR-383-5p ↑ Brain function	Rani et al. [25]
miR-146a	-	↓ miR-146 a ↑ Brain function	Zou et al. [26]